| conditions of system | Dose per dry weight of pulp and paper produced | Remarks |
| = | lb./ton | gr./metric ton | = |
| Heavily fouled | 0.15-0.35 | 75-175 | Boil out first, then dose with BIOBROM C-103L |
| Moderately fouled | 0.35-0.50 | 175-250 | Dose with BIOBROM C-103L on
continuous or intermittent basis |
| Slightly fouled | 0.15-0.35 | 75-175 | Dose continuously with BIOBROM C-103L until slime is controlled, then add on an intermittent basis to maintain control |